BU-207 Developmental Biology

Unit · year 2

BU-207 · Developmental Biology

Threads information · regulation25 lectures5 concepts

How a single cell builds a whole organism.

PREREQUISITES

L01	The Central Question of Development —
L02	From Zygote to Organism: An Overview —
L03	Cleavage and Blastula Formation —
L04	Gastrulation and the Germ Layers Induction
L05	Cell Fate, Determination, and Differentiation Differential gene expression
L06	Differential Gene Expression Differential gene expression
L07	Evidence: Nuclear Transfer and Cloning Differential gene expression
L08	Stem Cells and Potency Differential gene expression
L09	Cytoplasmic Determinants Differential gene expression
L10	Induction and Cell–Cell Signalling Induction
L11	The Spemann Organiser Induction
L12	Competence and Response Induction
L13	Positional Information Morphogen gradients
L14	Morphogen Gradients Morphogen gradients
L15	The French Flag Model Morphogen gradients
L16	Bicoid and Anterior–Posterior Patterning Morphogen gradients
L17	Segmentation Genes in Drosophila Hox genes and the body plan
L18	Hox Genes and the Body Plan Hox genes and the body plan
L19	Colinearity and Hox Conservation Hox genes and the body plan
L20	Homeotic Transformations Hox genes and the body plan
L21	Programmed Cell Death Apoptosis
L22	Apoptosis in Sculpting Structures Apoptosis
L23	The Apoptotic Machinery Apoptosis
L24	Evo-Devo: Development and Evolutionary Change Hox genes and the body plan
L25	Synthesis: One Genome, Many Cell Types Differential gene expression, Morphogen gradients

One genome gives rise to many cell types.

Concentration gradients supply positional information.

Master genes that specify anatomy.

Cells directing the fate of their neighbours.

Programmed cell death sculpts developing tissues.