Unit · year 2
BU-201 · Molecular Biology
Threads information24 lectures5 concepts
The molecular flow of genetic information from DNA to protein.
Lectures
| L01 | DNA as the Genetic Material — |
| L02 | Griffith, Avery, and Hershey–Chase — |
| L03 | The Central Dogma |
| L04 | Exceptions and Extensions to the Dogma |
| L05 | DNA Replication: The Problem |
| L06 | The Meselson–Stahl Experiment |
| L07 | Semiconservative Replication |
| L08 | The Replication Fork and Its Enzymes |
| L09 | Leading and Lagging Strands |
| L10 | Proofreading and Repair |
| L11 | Telomeres and the End-Replication Problem |
| L12 | Transcription: Initiation |
| L13 | Elongation and Termination |
| L14 | RNA Processing: Capping, Splicing, Polyadenylation |
| L15 | Alternative Splicing |
| L16 | The Genetic Code |
| L17 | Deciphering the Code: Nirenberg and Khorana |
| L18 | tRNA and the Adaptor Hypothesis |
| L19 | Translation: Initiation, Elongation, Termination |
| L20 | Protein Targeting and Post-Translational Modification |
| L21 | Point Mutations and Their Consequences |
| L22 | Frameshift and Chromosomal Mutations |
| L23 | Mutagens and Mutation Rate |
| L24 | Synthesis: Information Flow in the Cell |
Concepts in this unit
T-031
The central dogma
Information flows DNA to RNA to protein.
T-032
Semiconservative DNA replication
Each old strand templates a new complementary one.
T-033
Transcription
Copying a gene into messenger RNA.
T-034
Translation and the genetic code
Reading codons to build a polypeptide.
T-035
Mutations
How changes in DNA sequence alter proteins.