BU-301 Immunology

Unit · year 3

BU-301 · Immunology

Threads regulation · systems25 lectures5 concepts

How the body distinguishes self from non-self and remembers pathogens.

PREREQUISITES

L01	The Immune Problem: Self versus Non-Self —
L02	Physical and Chemical Barriers Innate and adaptive immunity
L03	Innate Immunity: Cells and Recognition Innate and adaptive immunity
L04	Pattern Recognition Receptors Innate and adaptive immunity
L05	Inflammation and the Complement System Innate and adaptive immunity
L06	Phagocytosis Innate and adaptive immunity
L07	Adaptive Immunity: The Distinguishing Features Innate and adaptive immunity
L08	Lymphocyte Development Clonal selection
L09	Clonal Selection Clonal selection
L10	Clonal Expansion and Effector Function Clonal selection
L11	Self-Tolerance and Its Failure Clonal selection
L12	Antibody Structure Antibody structure and diversity
L13	Antibody Classes and Their Functions Antibody structure and diversity
L14	V(D)J Recombination Antibody structure and diversity
L15	The Source of Antibody Diversity Antibody structure and diversity
L16	Somatic Hypermutation and Affinity Maturation Antibody structure and diversity
L17	MHC Class I and II MHC and antigen presentation
L18	Antigen Processing and Presentation MHC and antigen presentation
L19	T Cell Receptors and Activation MHC and antigen presentation
L20	Helper and Cytotoxic T Cells MHC and antigen presentation
L21	Primary and Secondary Responses Immunological memory
L22	Immunological Memory Immunological memory
L23	Vaccination and Its Basis Immunological memory
L24	Immune Dysfunction: Allergy, Autoimmunity, Immunodeficiency —
L25	Synthesis: Specificity, Diversity, and Memory Clonal selection, Immunological memory

Two coordinated layers of defence.

How lymphocytes specific to a pathogen are amplified.

Generating a near-limitless repertoire from limited genes.

Displaying cellular contents to T cells.

The basis of long-lasting immunity and vaccines.